Compound
liraglutide
Every Peptide Proof article that examines the evidence on liraglutide.
Do GLP-1s Affect Bone Density?
The published meta-analyses disagree with each other. A 25-study pooled analysis in people with type 2 diabetes found GLP-1 receptor agonists were lin…
Randomized controlled trialDoes Resistance Training Protect Muscle During GLP-1 Weight Loss?
The only completed randomized trial to combine supervised exercise with a GLP-1 drug found the combination cut body-fat percentage roughly twice as mu…
Human clinical trialHow Long Do People Actually Stay on GLP-1s?
Considerably less long than clinical trials suggest. In a large US commercial insurance claims analysis, only 32.3% of people starting a GLP-1 for obe…
Randomized controlled trialWhy Am I Still Hungry on a GLP-1?
In controlled feeding trials, semaglutide cut how much food people ate at a free-choice meal by roughly 35-39% compared with placebo, and reduced self…
Systematic reviewHow Much of the Weight Lost on GLP-1s Is Muscle?
Across 35 randomized trials, the median share of total weight loss coming from muscle-related measures was about 28% — but the range was enormous, fro…
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New research briefs, plainly written and fully sourced. No dosing advice, ever.